Nobel Prize in Medicine 2023

[mister_coffee]

Also (not paywalled):

https://www.nytimes.com/2022/01/15/heal ... =url-share

[mister_coffee]

I'm kind of surprised that this (mRNA vaccines) isn't being made into as big a deal as it actually is.

Before mRNA vaccines, we'd have no way to rapidly scale up manufacture of a vaccine. Now we do. Now the critical path part of the time to deploy a vaccine is going to be safety and efficacy testing, not building factories to grow vaccine. Well, at least for vaccines where mRNA can work.

There is also enormous potential for this technology for treatment of other diseases, included certain genetic diseases and cancer.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017382/

mRNA vaccines are also the likely first example of a medication based on nanotechnology. Where "nanotechnology" refers to a process where we can precisely construct very large molecules.

[PAL]

Saw them interviewed on the news. She seemed quite humble. Glad they got the recognition they deserve.
Thought I would comment about something other than....the Pool!

[mister_coffee]

Katalin Karikó and Drew Weissman

for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19

The discoveries by the two Nobel Laureates were critical for developing effective mRNA vaccines against COVID-19 during the pandemic that began in early 2020. Through their groundbreaking findings, which have fundamentally changed our understanding of how mRNA interacts with our immune system, the laureates contributed to the unprecedented rate of vaccine development during one of the greatest threats to human health in modern times. 

https://www.nobelprize.org/prizes/medic ... s-release/